Morning Shake

Hydrolyzed Bovine Collagen

Collagen is the most abundant protein in the body and offers us so many benefits, like maintaining the structural integrity of our skin, joints, tendons, muscles, hair, and more†. Unfortunately, we lose collagen as we age. Hydrolyzed bovine collagen is also a rich source of the amino acid glycine, which is important for detoxification, fighting inflammation, and protecting and repairing the gut†. We included this hydrolyzed bovine collagen from pasture-raised cows as part of the 10 Day Reset to provide a clean, easily digestible protein source with multifaceted benefits for longevity and optimal health.

Supportive Research:

• Oral Supplementation of Specific Collagen Peptides Has Beneficial Effects on Human Skin Physiology: A Double-Blind, Placebo-Controlled Study

• Multifarious Beneficial Effect of Nonessential Amino Acid, Glycine: A Review

• An Overview of the Beneficial Effects of Hydrolysed Collagen as a Nutraceutical on Skin Properties: Scientific Background and Clinical Studies

• A double-blind, placebo-controlled, randomised, clinical study on the effectiveness of collagen peptide on osteoarthritis.*

Organic Pea Protein

Protein has become an underappreciated macronutrient, but we need it to stay strong and functional, with a greater requirement as we age. Pea protein is a great plant-based option that is also hypoallergenic. It’s been shown to help with muscle strengthening and it’s a rich source of the amino acid arginine, which is necessary for nitric oxide production and plays an important role in cardiovascular health†. Pea protein is also a great plant-derived source of iron. 

Supportive Research:

• Pea proteins oral supplementation promotes muscle thickness gains during resistance training: a double-blind, randomized, Placebo-controlled clinical trial vs. Whey protein
• Arginine and endothelial and vascular health.

Organic Pumpkin Protein

Pumpkin seeds are a small but mighty superfood. Pumpkin protein is an excellent source of minerals like magnesium, iron, and zinc. It’s also high in antioxidants and works as a natural anti-inflammatory, while providing all the essential amino acids to make it a complete protein, complementing those available in both pea protein and collagen†. 

Supportive Research:

• Amino acid composition and antioxidative properties of hydrolysed pumpkin (Cucurbita pepo L.) oil cake protein

Organic MCT

MCT stands for medium-chain triglycerides. These are super healthy fats your body can immediately use as fuel, bypassing the process other fats need to go through, and it’s been found to increase satiation cues and burn fat, helping with weight loss†. MCT oil is also a great functional ingredient for gut health—it supports beneficial bacteria and improves intestinal permeability†. Plus, MCT’s encourage the production of ketone bodies that give the brain quick-burning energy and may even reduce the risk of neurodegenerative diseases†.

Supportive Research:  

• Weight-loss diet that includes consumption of medium-chain triacylglycerol oil leads to a greater rate of weight and fat mass loss than does olive oil.

• Gut Microbiota and Metabolic Health: The Potential Beneficial Effects of a Medium Chain Triglyceride Diet in Obese Individuals
• Can ketones compensate for deteriorating brain glucose uptake during aging? Implications for the risk and treatment of Alzheimer's disease.

Avocado Oil Powder

Avocado oil is an incredibly healthy fat. 70% of it is a heart-healthy monounsaturated fat called oleic acid. Avocados have been found to have lipid-lowering, antihypertensive, antidiabetic, anti-obesity, antiatherosclerotic, and cardioprotective effects that reduce the overall risk for metabolic syndrome, type 2 diabetes, and the associated complications†. It’s also very rich in antioxidants like lutein and zeaxanthin, which support good eyesight and enhance cognition†.

Supportive Research (oil):

• Carotenoid absorption from salad and salsa by humans is enhanced by the addition of avocado or avocado oil.

Supportive Research (avocado): 

• New research examines avocados' potential impact on cognitive health in older adultsAvocado consumption is associated with better diet quality and nutrient intake, and lower metabolic syndrome risk in US adults

L-Leucine

L-Leucine is a branched-chain amino acid that’s been associated with increasing lean muscle mass and functional strength, improving exercise performance, and decreasing perceived exertion†.

Supportive Research 

• Double-blind, placebo-controlled pilot trial of L-Leucine-enriched amino-acid mixtures on body composition and physical performance in men and women aged 65–75 years

• Effects of dietary leucine supplementation on exercise performance

Organic gum acacia 

This is an edible plant-derived fiber that naturally thickens our Morning Shake mix. Also known as gum arabic, gum acacia has prebiotic properties that support good bacteria in the gut and it’s also been found to increase satiety and reduce overcall caloric intake†. 

Supportive Research 

• Gum arabic establishes prebiotic functionality in healthy human volunteers in a dose-dependent manner

• Evaluation of satiety enhancement, including compensation, by blends of gum arabic. A methodological approach 

Multi

B Vitamins

Methylation is a biochemical process that regulates our cardiovascular, neurological, reproductive, and detoxification systems and it’s one several B vitamins play a big part in. Many multivitamins out there use synthetic forms of these precious vitamins (like folic acid, cyanocobalamin, and pyridoxine hydrochloride), when the methylated forms (think 5-methyltetrahydrofolate, methylcobalamin, and pyridoxal-5-phosphate) are more readily available and active†. Considering that about 60% of people in the US aren’t effective at methylating, meaning they can’t use those synthetic forms effectively, it’s important to take the right kind of B vitamins for optimal health†.

Supportive Research

• Comparative Bioavailability and Utilization of Particular Forms of B12 Supplements With Potential to Mitigate B12-related Genetic Polymorphisms

• [Effectiveness of oral vitamin B12 therapy for pernicious anemia and vitamin B12 deficiency anemia].

• Folic Acid Supplementation and Pregnancy: More Than Just Neural Tube Defect Prevention

• Plasma Pyridoxal-5-Phosphate Is Inversely Associated with Systemic Markers of Inflammation in a Population of U.S. Adults1,2,3

Vitamin A

Carotenoids are nutrients our body can turn into vitamin A or use as antioxidants, and we rely on them for healthy eyes, strong mucous membranes, immune function, skin health, and maintaining cognition†. They’ve even been found to help with a healthy weight and body composition†.

Supportive Research

•  Nutritional Intervention to Prevent Alzheimer’s Disease: Potential Benefits of Xanthophyll Carotenoids and Omega-3 Fatty Acids Combined

• Supplementation with beta-carotene or a similar amount of mixed carotenoids protects humans from UV-induced erythema.
• Effects of Mixed Carotenoids on Adipokines and Abdominal Adiposity in Children: A Pilot Study.

Vitamin D

We can synthesize vitamin D from the sun, using our liver and kidneys, but many of us spend large amounts of time indoors and don’t necessarily convert it into its active form efficiently. We need vitamin D for balanced hormones, fighting disease-causing inflammation, and so much more†. With the rise in autoimmunity, vitamin D is especially important to protect and support a high-functioning immune system†. 

Supportive Research

• Vitamin D and the Immune System

• 1,25-Dihydroxyvitamin D3 Restrains CD4+ T Cell Priming Ability of CD11c+ Dendritic Cells by Upregulating Expression of CD31

Vitamin K

Vitamin K was a forgotten nutrient, but not anymore. It’s finally being recognized for its role in bone density and proper mineral delivery and calcification, and it’s also been shown to improve insulin sensitivity and inhibit the growth of cancer cells†.

Supportive Research 

• The health benefits of vitamin K

• Dietary intake of vitamin K in relation to bone mineral density in Korea adults: The Korea National Health and Nutrition Examination Survey (2010–2011)

• Vitamin K intake and hip fractures in women: a prospective study

† Statements made on this website have not been evaluated by the U.S. Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease. Information provided by this website or this company is not a substitute for individual medical advice. 

Mag Zinc

Magnesium Bisglycinate

Magnesium is an essential mineral for over 300 reactions in the body, and many of us are deficient due to poor diet and declining soil quality. It’s especially important for regulating healthy muscle and nerve function, mood, blood pressure, and blood sugar levels†.

Supportive Research

• Magnesium Intake and Incidence of Metabolic Syndrome Among Young Adults

• Effects of Magnesium Supplementation on Blood Pressure: A Meta-Analysis of Randomized Double-Blind Placebo-Controlled Trials.

• Role of magnesium supplementation in the treatment of depression: A randomized clinical trial

Zinc Gluconate

Zinc is an important mineral for the immune system but it may also helps to stabilize blood sugar levels, and support skin, eye, reproductive, and heart health†.

Supportive Research

• Zinc lozenges and the common cold: a meta-analysis comparing zinc acetate and zinc gluconate, and the role of zinc dosage

• Zinc Lozenges Reduce the Duration of Common Cold Symptoms

• The role of zinc in reproduction. Hormonal mechanisms.

Detox

Milk Thistle Extract

An ancient herb that especially supports and protects the liver, milk thistle is rich in a compound called silymarin that has antioxidant and tissue regenerative properties†. It can help us defend ourselves more effectively against toxins†.

Supportive Research

• “Silymarin”, a Promising Pharmacological Agent for Treatment of Diseases

• Heavy metals detoxification: A review of herbal compounds for chelation therapy in heavy metals toxicity

Glutathione

Dubbed the “master” antioxidant, glutathione regulates immune function and oxidative stress and is a powerful nutrient for detoxification†. It’s also required to make DNA. Glutathione helps us regenerate other essential antioxidants and can benefit glucose metabolism†. 

Supportive Research 

• Randomized controlled trial of oral glutathione supplementation on body stores of glutathione

• The relationship between the level of glutathione, impairment of glucose metabolism and complications of diabetes mellitus

Green Tea Extract

Green tea is a jack of all trades—it has antioxidant, anti-inflammatory, and anti-carcinogenic properties while providing protection to the brain and liver†. It’s also a major detoxifier, as the phytochemicals it contains can boost our endogenous detoxification enzymes†.

Supportive Research 

• Green Tea Boosts Production Of Detox Enzymes, Rendering Cancerous Chemicals Harmless

• An Update on the Health Benefits of Green Tea

Sleep

GABA

GABA is an inhibitory neurotransmitter, meaning it can induce relaxation†. It’s a useful supplement to support falling asleep and staying asleep so you can wake up rested†.

Supportive Research

• Safety and Efficacy of Gamma-Aminobutyric Acid from Fermented Rice Germ in Patients with Insomnia Symptoms: A Randomized, Double-Blind Trial

• GABA and l-theanine mixture decreases sleep latency and improves NREM sleep

L-theanine

L-theanine is an amino acid found in high amounts in tea that can positively modify brain waves  to support a more relaxed state and the key neurotransmitters involved in mood, focus, and memory†.

Supportive Research

• L-theanine, a natural constituent in tea, and its effect on mental state

Melatonin

Supportive Research

• Melatonin in Patients with Reduced REM Sleep Duration: Two Randomized Controlled Trials 

Nature Partner Journals: Aging and Mechanisms of Disease Publishes Elysium’s Clinical Trial Studying Basis

Abstract

The first-in-humans, double-blind, placebo-controlled, randomized study assessed the safety and efficacy of taking repeat doses of Basis — a combination of nicotinamide riboside (NR) and pterostilbene — in a population of 120 healthy adults ages 60-80. The results? Regular doses of Basis increased NAD+ levels by an average of 40 percent.

Introduction

Metabolism, Aging, and NAD+

A properly functioning metabolism is essential to health and longevity. In the scientific sense of the word, metabolism refers to the sum of every chemical reaction that happens inside the body, an enormous web of interactions on the molecular level that aim to keep the you in what biologists call homeostasis: a state of balance, best illustrated by our near constant body temperature, which persists even in a wide range of circumstances. This is all made possible by an elegant choreography between coenzymes (or, “helper molecules”) and specific proteins acting as metabolic sensors, attuned to, and responding to ambient conditions in the cell and the body as a whole. The coenzyme nicotinamide adenine dinucleotide (NAD+) and a family of proteins called sirtuins make up an important part of this choreography.

NAD+ in Energy Creation, Genome Integrity, and More

First discovered in 1906, NAD+ is a coenzyme found in all living cells, and it has two main categories of roles in the body. One is turning nutrients into energy. In that process NAD+ transfers electrons in redox reactions to help synthesize ATP, the energy currency of the cell. Importantly, NAD+ isn’t “used up” or consumed in creating energy. In the other category of roles, NAD+ works with proteins to carry out essential biological processes like DNA damage repair, mitochondrial function, maintaining chromosomal integrity, gene expression, epigenetic and posttranslational modifications, and calcium signaling. Sirtuins are some of the proteins that regulate these processes, especially those that help keep the cell healthy during stressful conditions, including aging.

First discovered in 1906, NAD+ is a coenzyme found in all living cells, and it has two main categories of roles in the body. One is turning nutrients into energy. In that process NAD+ transfers electrons in redox reactions to help synthesize ATP, the energy currency of the cell. Importantly, NAD+ isn’t “used up” or consumed in creating energy. In the other category of roles, NAD+ works with proteins to carry out essential biological processes like DNA damage repair, mitochondrial function, maintaining chromosomal integrity, gene expression, epigenetic and posttranslational modifications, and calcium signaling. Sirtuins are some of the proteins that regulate these processes, especially those that help keep the cell healthy during stressful conditions, including aging.